| CAS NO: | 553-12-8 |
| 包装: | 100mg |
| 市场价: | 500元 |
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 562.66 |
| Cas No. | 553-12-8 |
| Formula | C34H34N4O4 |
| Solubility | insoluble in H2O; insoluble in EtOH; insoluble in DMSO |
| Canonical SMILES | O=C(CCC1=C2/C=C3C(CCC(O)=O)=C(C(/C=C(C(C)=C/4C=C)\NC4=C/C5=N/C(C(C=C)=C5C)=C\C(N2)=C1C)=N/3)C)O |
| 运输条件 | 蓝冰运输或根据您的需求运输。 |
| 一般建议 | 为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同厂家不同批次半岛bd体育手机客户端 溶解度各有差异，仅做参考。若实验所需浓度过大至半岛bd体育手机客户端 溶解极限，请添加助溶剂助溶或自行调整浓度。溶液形式一般不宜长期储存，请尽快用完。 |
Protoporphyrin IX, widely distributed in all living cells in small amounts, is the final intermediate of the heme biosynthetic pathway. Chelation of Protoporphyrin IX with iron forms heme, which is a constituent of hemoproteins that play essential roles in a variety of biological events, such as oxygen transport, cellular oxidations and reductions, electron transport, as well as drug metabolism. Based on its photodynamic effects, Protoporphyrin IX has also been explored for cancer diagnosis and treatment. However, accumulation of Protoporphyrin IX in human porphyrias can lead to a series of symptoms including skin photosensitivity, hepatobiliary damage, biliary stones, and even liver failure.
Reference:
1. Sachar M, Anderson KE, Ma X. Protoporphyrin IX: the Good, the Bad, and the Ugly. Journal of Pharmacology and Experimental Therapeutics, 2016, 356(2): 267-275.
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