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endo-BCN-PEG2-acid
本半岛bd体育手机客户端 不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
endo-BCN-PEG2-acid图片
CAS NO:1993134-72-7
包装:100mg
市场价:6723元

半岛bd体育手机客户端 介绍
endo-BCN-PEG2-acid 是基于 PEG 的 PROTAC linker,可用于 PROTAC 的合成。
Cas No.1993134-72-7
分子式C18H27NO6
分子量353.41
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端 描述

endo-BCN-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[1]. Sano K, et al. Short PEG-linkers improve the performance of targeted, activatable monoclonal antibody-indocyanine green optical imaging probes. Bioconjug Chem. 2013 May 15;24(5):811-6.

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