半岛bd体育手机客户端
名称: | 索拉非尼 |
CAS: | 284461-73-0 |
分子式: | C21H16ClF3N4O3 |
分子量: | 464.83 |
纯度: | ≥98% |
溶解性: | DMSO |
存储: | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
Target: | IC50: 6 nM (Raf-1), 20 nM (VEGFR-3), 22 nM (BRAF), 57 nM (PDGFR-β), 58 nM (Flt3), 68 nM (c-KIT), 90 nM (VEGFR-2)[1] |
描述: | Sorafenib is a potent multikinase inhibitor with IC50 of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively. |