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名称： | 吡啶酮6 |
| CAS： | 457081-03-7 |
| 分子式： | C18H16FN3O |
| 分子量： | 309.34 |
| 纯度： | >98% |
| 溶解性： | DMSO |
| 存储： | Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
| 研究领域： | Cancer |
| Target： | JAK2, 1 nM (IC50); Tyk2, 1 nM (IC50); JAK3, 5 nM (IC50); Murine; JAK1, 15 nM (IC50) |
| 描述： | Pyridone 6 is a pan-JAK inhibitor, which potently inhibits the JAK kinase family, with IC50s of 1 nM for JAK2 and TYK2, 5 nM for JAK3, and 15 nM for JAK1, while displaying significantly weaker affinit |
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