K-Ras G12C-IN-1是突变型K-Ras G12C不可逆小分子抑制剂。
| Cas No. | 1629265-17-3 |
| Canonical SMILES | ClC(C=C(OC)C(NCC(N1CCN(C(C=C)=O)CC1)=O)=C2)=C2C3=CC=CC=C3Cl |
| 分子式 | C22H23Cl2N3O3 |
| 分子量 | 448.34 |
| 溶解度 | DMSO: ≥ 40 mg/mL (89.22 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
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描述 | K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C extracted from patent WO 2014152588 A1.IC50 value:Target: K-ras G12C inhibitor |
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