Z-VAD-FMK(Caspase Inhibitor VI) - 半岛电竞官方网址

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Z-VAD-FMK(Caspase Inhibitor VI)

本半岛bd体育手机客户端不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:	161401-82-7
规格:	≥98%

包装与价格：

半岛bd体育手机客户端介绍

理化性质和储存条件

Molecular Weight (MW)	453.46
Formula	C21H28FN3O7
CAS No.	161401-82-7
Storage	-20℃ for 3 years in powder form
Storage	-80℃ for 2 years in solvent
Solubility (In vitro)	DMSO: 90 mg/mL (198.47 mM)
	Water:<1 mg/mL (slightly soluble or insoluble)
	Ethanol: N/A
SMILES	O=C(N[C@H](C(N[C@@H](C)C(N[C@@H](CC(O)=O)C(CF)=O)=O)=O)C(C)C)OCC1=CC=CC=C1
Chemical Name	Z-VAD(OH)-FMK; Z-VAD FMK L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxymethyl)-3-fluoro-2-oxopropyl]-

实验参考方法

In Vitro	Z-VAD(OH)-FMK is the non-methylated form of Z-VAD-FMK, and useful in studies including recombinant, or purified enzymes. As an irreversible general caspase inhibitor, it is useful for studies involving recombinant, isolated, and purified caspase enzymes. Unlike Caspase Inhibitor I, this inhibitor does not require pretreatment with esterase for in vitro studies. A 10 mM (1 mg/221 μl) solution of Caspase Inhibitor VI in DMSO is also available.
In Vivo	N/A
Animal model	N/A
Formulation & Dosage	N/A
References	Garcia-Calvo M, et al. J Biol Chem. 1998, 273(49), 32608-32613.

生物活性

Inhibition of caspases by tetrapeptide aldehydes. J Biol Chem. 1998 Dec 4;273(49):32608-13.

Inhibition of caspases by CrmA. J Biol Chem.1998 Dec 4;273(49):32608-13.