| CAS NO: | 64984-31-2 |
| 规格: | ≥98% |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| 250mg | 电议 |
| 500mg | 电议 |
| 1g | 电议 |
| Molecular Weight (MW) | 181.21 |
|---|---|
| Formula | C8H7NO2S |
| CAS No. | 64984-31-2 |
| Storage | -20℃ for 3 years in powder form |
| -80℃ for 2 years in solvent | |
| Solubility (In vitro) | DMSO: 36 mg/mL (198.7 mM) |
| Water: <1 mg/mL (slightly soluble or insoluble) | |
| Ethanol: N/A | |
| Solubility (In vivo) | 1% DMSO+30% polyethylene glycol+1% Tween 80:10 mg/mL |
| Synonyms | Pifithrin-μ; Pifithrin μ; Pifithrinμ; 2-Phenylethynesulfonamide; PFT-μ; PFT μ; PFTμ; NSC303580; NSC-303580; NSC 303580 |
| General | Pifithrin-μ (40 mg/kg, ip) produces protective effect from p53-dependent apoptosis in C57B1/6J mice of 8 or 9 Gy of total body gamma radiation. In a xenograft mouse model, Pifithrin-μ significantly enhances the inhibition of TRAIL on MiaPaca-2 tumor growth |
|---|---|
| Animal model | C57B1/6J mice. |
| Formulation | DMSO |
| Dosages | 40 mg/kg |
| Administration | i.p |
| References | [1] Strom E, et al. Nat Chem Biol. 2006, 2(9), 474-479. |
 Blood Cancer J. 2011 Jul; 1(7): e28. |
|
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