LTβR-IN-1 - 半岛电竞官方网址

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LTβR-IN-1

本半岛bd体育手机客户端不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2189366-77-4

包装与价格：

半岛bd体育手机客户端介绍

LTβR-IN-1 是一种有效的，选择性淋巴毒素β受体 (LTβR) 抑制剂，IC50 为 10 μM。LTβR-IN-1 对 TWEAK 刺激的 p52 易位测定中的 IC50 为 10 μM，LTβR-IN-1 不改变 TNF-α 诱导的 p65 核转位。

Cas No.	2189366-77-4
分子式	C18H16N4O2
分子量	320.35
溶解度	DMSO : 125 mg/mL (390.20 mM; Need ultrasonic)
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端描述	LTβR-IN-1 is a potent, selective lymphotoxin β receptor (LTβR) inhibitor with an IC50 of 10 μM. LTβR-IN-1 is potent in TWEAK-stimulated p52 translocation assays with an IC50 of 10 μM and did not alter TNF-α-induced p65 nuclear translocation[1]. [1]. Henry KL, et al. CDK12-mediated transcriptional regulation of noncanonical NF-κB components is essential for signaling. Sci Signal. 2018 Jul 31;11(541).