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Abafungin
本半岛bd体育手机客户端 不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Abafungin图片
CAS NO:129639-79-8
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议

半岛bd体育手机客户端 介绍
阿巴芬净是一种抗真菌剂,可抑制甾醇侧链 C-24 位点的甲基转移,由甾醇-C-24-甲基转移酶催化。
Cas No.129639-79-8
别名阿巴芬净,BAY-W-6341
Canonical SMILESCC1=CC(C)=CC=C1OC2=C(C=CC=C2)C3=CSC(NC4=NCCCN4)=N3
分子式C21H22N4OS
分子量378.5
溶解度DMF: 10 mg/mL,DMSO: 2.5 mg/mL,Ethanol: 0.3 mg/mL,PBS (pH 7.2): 0.3 mg/mL
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端 描述

Abafungin is an antifungal agent.1It is active against a variety of dermatophytes, yeast, molds, and other fungi (MICs = ≤0.06-2, 0.5-16, ≤0.06-1, and 0.25-8 µg/ml, respectively). Abafungin inhibits ergosterol biosynthesis, as well as acts directly on the fungal cell membrane to induce cell death.

1.Borelli, C., Schaller, M., Niewerth, M., et al.Modes of action of the new arylguanidine abafungin beyond interference with ergosterol biosynthesis and in vitro activity against medically important fungiChemotherapy54(4)245-259(2022)

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