CP 67804 enhances topoisomerase II-mediated DNA cleavage. It suggests that these quinolone analogues represent a novel class of topoisomerase II-targeted drugs which have potential as antineoplastic agents. References: Robinson MJ, Martin BA, Gootz TD, McGuirk PR, Moynihan M, Sutcliffe JA, Osheroff N. Effects of quinolone derivatives on eukaryotic topoisomerase II. A novel mechanism for enhancement of enzyme-mediated DNA cleavage. J Biol Chem. 1991 Aug 5;266(22):14585-92. PubMed PMID: 1650363.

纯度：≥98%

CAS：103978-08-1