ITH-12575 is a Mitochondrial Na+/Ca2+ exchange (mNCX) inhibitor. ITH12575 reduced Ca(2+) influx through CALHM1 at low micromolar concentrations. References: Moreno-Ortega AJ, Martínez-Sanz FJ, Lajarín-Cuesta R, de Los Rios C, Cano-Abad MF. Benzothiazepine CGP37157 and its 2'-isopropyl analogue modulate Ca2+ entry through CALHM1. Neuropharmacology. 2015 Aug;95:503-10. doi: 10.1016/j.neuropharm.2015.02.016. PubMed PMID: 25908402.

纯度：≥98%

CAS：1802013-08-6