L-368899 is a potent, non-peptide and orally bioavailable oxytocin receptor antagonist (IC50 = 8.9 nM) that exhibits > 40-fold selectivity over vasopressin V1a and V2 receptors (IC50 are 370 and 570 nM respectively). L-368,899 HCl antagonizes oxytocin-induced uterine contractions in vitro and in vivo. References: Smith AL, Freeman SM, Voll RJ, Young LJ, Goodman MM. Carbon-11 N-methyl alkylation of L-368,899 and in vivo PET imaging investigations for neural oxytocin receptors. Bioorg Med Chem Lett. 2013 Feb 1;23(3):902-6. doi: 10.1016/j.bmcl.2012.10.116. PubMed PMID: 23270988; PubMed Central PMCID: PMC3756487.

纯度：≥98%

CAS：160312-62-9