An endogenous vasodilator
货号:ajcx26676
CAS:N/A
分子式:C50H73N15O11 • XCF3COOH
分子量：1060.2
溶解度:DMF: 20 mg/mL,DMSO: 10 mg/mL,Ethanol: 5 mg/mL,PBS (pH 7.2): 1 mg/mL
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Bradykinin is a 9-amino acid peptide that dilates blood vessels and consequently reduces blood pressure by inducing the release of prostacyclin, nitric oxide, and endothelium-derived hyperpolarizing factor.^1,2,3It also contracts non-vascular smooth muscle in the bronchus and gastrointestinal tract, increases vascular permeability, and is involved in the mechanism of pain mediation.^4,5,6The discovery of bradykinin-potentiating peptides from snake venom led to the discovery of a class of highly-effective anti-hypertensive drugs, the ACE inhibitors, which have been shown to prevent angiotensin-converting enzyme’s inactivation of bradykinin.⁷

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