Potent and reversible NIMA related kinase 2 (Nek2) inhibitor
货号:ajcx26946
CAS:1507367-00-1
分子式:C15H12N6O
分子量：292.3
溶解度:DMSO: 25 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Potent and reversible NIMA related kinase 2 (Nek2) inhibitor (IC50 = 56 nM). Induces increased mitotic abnormalities and mitotic delay. Cell permeable and active in vivo.

Lebraud et al (2014) Model system for irreversible inhibition of Nek2: thiol addition to ethynylpurines and related substituted heterocycles. Org.Biomol.Chem. 12 141 PMID:24213855