规格: | 98% |
分子量: | 678 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
Background:
L-319 is an ionizable (pKa= 6.38) and biodegradable lipid that has been used in the formation of lipid nanoparticles.1Administration of mouse factor VII-targeting siRNA in L-319-containing lipid nanoparticles induces factor VII silencing in mice.
1.Maier, M.A., M., J., Matsuda, S., et al.Biodegradable lipids enabling rapidly eliminated lipid nanoparticles for systemic delivery of RNAi therapeuticsMol. Ther.21(8)1570-1578(2013)