Chloroguanabenz is an antiprion agent and a derivative of the α2-adrenergic receptor agonist guanabenz.
货号:ajcx18266
CAS:N/A
分子式:C8H7Cl3N4•C2H4O2
分子量：325.6
溶解度:DMSO: soluble,Ethanol: soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Chloroguanabenz is an antiprion agent and a derivative of the α2-adrenergic receptor agonist guanabenz . It inhibits prion formation in yeast and mammalian cell-based assays. Chloroguanabenz reduces the levels of both soluble and aggregated forms of the truncated Huntingtin derivative Htt48 in an HEK293T cellular model of Huntington's disease.