规格: | 98% |
分子量: | 531.49 |
包装 | 价格(元) |
10mg | 电议 |
50mg | 电议 |
Background:
Topoisomerase I inhibitor. Forms stable DNA-topoisomerase complexes during DNA replication and induces cell cycle arrest in the G2/M phase. Inhibits growth of a range of cancer cell lines in vitro, as well as of ovarian and leukemia tumors in vivo.
Kim et al (2015) Anticancer effects of CKD-602 (Camtobell®) via G2/M phase arrest in oral squamous cell carcinoma cell lines. Oncol.Lett. 9 136 PMID:25435947 |Jung et al (2006) The synergism between Belotecan and cisp. in gastric cancer. Cancer Res.Treat. 38 159 PMID:19771277