MRGPRX2 agonist
货号:ajcx27542
CAS:2089389-15-9
分子式:C18H21N5
分子量：307.4
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Mas-related G protein-coupled receptor X2 (MRGPRX2) agonist (EC50 = 0.74 μM). Displays selectivity for MRGPRX2 over 350 other GPCRs, including MRGPRX1. Induces intracellular calcium release and degranulation in LAD2 mast cells in vitro. Negative control (S)-ZINC 3573 also available.

Lansu et al (2017) In silico design of novel probes for the atypical opioid receptor MRGPRX2. Nat.Chem.Biol. 13 529 PMID:28288109