LY222306是甘氨酰胺核糖核苷酸甲酰转移酶((GARFT))的抑制剂,Ki值为0.77nM。
货号:ajcx13036
CAS:154446-98-7
分子式:C19H23N5O7
分子量:433.42
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货Background:
LY 222306 is a glycinamide ribonucleotide formyltransferase (GARFT) inhibitor with a Ki of 0.77 nM.
[1]. Habeck LL, et al. A novel class of monoglutamated antifolates exhibits tight-binding inhibition of human glycinamide ribonucleotide formyltransferase and potent activity against solid tumors. Cancer Res. 1994 Feb 15;54(4):1021-6.