(Rac)-BL-918是BL-918的消旋体。BL-918是ULK1的有效激活剂,可诱导细胞保护性自噬,有治疗帕金森病的潜力。
货号:ajcx13572
CAS:N/A
分子式:C23H15F8N3OS
分子量:533.44
溶解度:DMSO : ≥ 125 mg/mL (234.33 mM);H2O :< 0.1 mg/mL (insoluble)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
(Rac)-BL-918 is the racemate of BL-918. BL-918 is a potent activator of UNC-51-like kinase 1 (ULK1), inducing cytoprotective autophagy for Parkinson's disease treatment[1].
[1]. Ouyang L, et al. Small-Molecule Activator of UNC-51-Like Kinase 1 (ULK1) That Induces Cytoprotective Autophagy for Parkinson's Disease Treatment. J Med Chem. 2018 Apr 12;61(7):2776-2792.