An orally active selective inhibitor of human calpains 1 and 2
货号:ajcx13096
CAS:1254698-46-8
分子式:C25H27N3O4
分子量：433.5
溶解度:DMSO: 8.33 mg/mL (19.22 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Alicapistat (ABT-957) is an orally active selective inhibitor of human calpains 1 and 2 for the potential use in the treatment of Alzheimer's disease (AD).

[1]. Lon HK, et al. Pharmacokinetics, Safety, Tolerability, and Pharmacodynamics of Alicapistat, a Selective Inhibitor of Human Calpains 1 and 2 for the Treatment of Alzheimer Disease: An Overview of Phase 1 Studies. Clin Pharmacol Drug Dev. 2018 Jul 27.