EMD638683 (S-Form)是SGK1抑制剂,IC50>300 nM。
CAS:1184940-46-2
分子式:C18H18F2N2O4
分子量:364.34
纯度:98%
存储:Store at -20°C
Background:
EMD638683 S-Form is the S-form of EMD638683. EMD638683 is a highly selective SGK1 inhibitor with IC50 of 3 μM.
[1]. Ackermann TF, et al. EMD638683, a novel SGK inhibitor with antihypertensive potency. Cell Physiol Biochem. 2011;28(1):137-46.
[2]. Sgk1 inhibitors for the prophylaxis and/or therapy of viral diseases and/or carcinomas US 20110060050 A1