Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.
CAS:183509-23-1
分子式:C20H32O3
分子量:320.5
纯度:98%
存储:Store at -20°C
Background:
Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 16-HETE is a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation that demonstrates stereospecific biological activity. 16(S)-HETE inhibits proximal tubule ATPase activity by as much as 60% at a concentration of 2 µM.