| CAS NO: | 2260791-14-6 |
| 规格: | 98% |
| 分子量: | 604.09 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
Background:
OSMI-4 is a low nanomolar O-GlcNAc transferase (OGT) inhibitor, with an EC50 of 3 μM in cells.
OSMI-4 (4b) is the best OGT inhibitor reported to date, with a ～3 μM EC50 in cells, making it especially attractive for probing OGT’s complex biology[1].
[1]. Martin SES, et al. Structure-Based Evolution of Low Nanomolar O-GlcNAc Transferase Inhibitors. J Am Chem Soc. 2018 Oct 24;140(42):13542-13545.
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