Motilin is a polypeptide hormone that stimulates gastric motility through release in the small intestine and into the general circulation during fasting.
CAS:9072-41-7
分子式:C120H188N34O35S
分子量:2699.1
纯度:98%
存储:Store at -20°C
Background:
Motilin is a polypeptide hormone that stimulates gastric motility through release in the small intestine and into the general circulation during fasting. In isolated rabbit duodenal segments, porcine motilin (10 nM-1 uM) induced phasic contractions and acetylcholine release from enteric neurons (EC50 = 2.5 nM). Formulations containing motilin are used to increase gastrointestinal motility in patients with diabetic gastroparesis, often in combination with erythromycin , an antibiotic and agonist at the motilin receptor.