CAS NO: | 14042-01-4 |
规格: | 98% |
分子量: | 85 |
包装 | 价格(元) |
1mL | 电议 |
5mL | 电议 |
Background:
Peroxynitrite is formed in vivo by the reaction of NO with superoxide.[1],[2],[3] It is a powerful oxidizing agent that can initiate lipid peroxidation, oxidize sulfhydryls, and nitrate the aromatic residues of proteins.
Reference:
[1]. Pryor, W.A., and Squadrito, G.L. The chemistry of peroxynitrite: A product from the reaction of nitric oxide with superoxide. American Journal of Physiology 268, L699-L722 (1995).
[2]. Beckman, J.S., and Koppenol, W.H. Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and the ugly. Am. J. Physiol. 271(5 Pt 1), C1424-C1437 (1996).
[3]. Koppenol, W.H., Moreno, J.J., Pryor, W.A., et al. Peroxynitrite, a cloaked oxidant formed by nitric oxide and superoxide. Chemical Research in Toxicology 5, 834-842 (1992).