E3ligaseLigand-LinkerConjugates13是用于PROTAC技术的化合物,其结合了E3连接酶配体和连接桥。
CAS:2010159-45-0
分子式:C28H39N7O6S
分子量:601.72
纯度:98%
存储:Store at -20°C
Background:
E3 ligase Ligand-Linker Conjugates 13 is a synthesized compound that incorporates an E3 ligase ligand and a linker used in PROTAC technology.
E3 ligase Ligand-Linker Conjugates 13 incorporates a VHL ligand and a linker. The ligand named VH032 is a potent and specific VHL ligand[1].
[1]. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.