| CAS NO: | 851378-93-3 |
| 规格: | 98% |
| 分子量: | 318.5 |
| 包装 | 价格(元) |
| 25ug | 电议 |
| 50ug | 电议 |
| 100ug | 电议 |
| 500ug | 电议 |
Background:
Eicosapentaenoic acid is converted to epoxyeicosatetraenoic acids (EpETEs) by several cytochrome P450 isoforms. The major product of this epoxygenase pathway, (±)17(18)-EpETE , relaxes vascular and airway smooth muscle by activating large conductance Ca2+-activated K+ (BKCa) channels by directly interacting with BKα channel subunits. (±)8(9)-EpETE is an epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo. The biological actions and physiological effects of this epoxide remain to be determined.
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