1,2,3,6-Tetragalloylglucose是有效的、UDP-葡萄糖醛酸转移酶1家族,多肽A1(UGT1A1)的抑制剂,其Ki值为1.68μM。
CAS:79886-50-3
分子式:C34H28O22
分子量:788.57
纯度:98%
存储:Store at -20°C
Background:
1,2,3,6-Tetragalloylglucose is a potent UDP glucuronosyltransferase 1 family, polypeptide A1 (UGT1A1) inhibitor, with a Ki of 1.68 μM[1].
Ki: 1.68 μM (UGT1A1)[1].
[1]. Park JB, et al. Identification and characterization of in vitro inhibitors against UDP-glucuronosyltransferase 1A1 in uva-ursi extracts and evaluation of in vivo uva-ursi-drug interactions. Food Chem Toxicol. 2018 Oct;120:651-661.