PROTAC MDM2 Degrader-2 是一种 PROTAC 类的 MDM2 降解剂。PROTAC MDM2 Degrader-2 由 MDM2 抑制剂,linker 和 E3 泛素连接酶 MDM2 配体组成。
CAS:2249944-99-6
分子式:C70H76Cl4N10O12
分子量:1391.22
纯度:98%
存储:Store at -20°C
Background:
PROTAC MDM2 Degrader-2 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader-2 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase[1].
[1]. Method of inducing of self-degradation of MDM2 using E3 ubiquitin ligase dimer amide small molecule PROTACs. CN108610333A.