生物活性
Solithromycin是一种新型的酮内酯抗生素。Solithromycin（CAS 760981-83-7）可用于抗感染，并且有望成为20多年来可用于静脉，口服和儿科悬浮液制剂的首个大环内酯类抗生素。
化学数据
| 目录号 | A14031 |
| M. Wt | 845.01 |
| Formula | C43H65FN6O10 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. | 760981-83-7 |
| Synonyms | CEM 101, CEM-101, OP-1068, Solithromycin, UNII-9U1ETH79CK |
| SMILES | CC[C@@H]1[C@@]2([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H](C(=O)[C@](C(=O)O1)(C)F)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)OC)C)C)N(C(=O)O2)CCCCN4C=C(N=N4)C5=CC=C(C=C5)N)C |
溶解度
| In vitro | DMSO | 87 mg/mL (102.96 mM) |
| Water | Insoluble |
| Ethanol | 22 mg/mL |
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
| 0.1 mM | 11.83 mL | 59.17 mL | 118.34 mL |
| 0.5 mM | 2.37 mL | 11.83 mL | 23.67 mL |
| 1 mM | 1.18 mL | 5.92 mL | 11.83 mL |
| 5 mM | 0.24 mL | 1.18 mL | 2.37 mL |
*The above data is based on the productmolecular weight 845.01. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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