SSR128129E free acid is an orally bioavailable and allosteric FGFR inhibitor with an IC50 of 1.9 μM for FGFR1. References: Bono F, et al. Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties. Cancer Cell. 2013 Apr 15;23(4):477-88.
纯度:≥98%
CAS:848463-13-8