Laninamivir trifluoroacetate
(Inavir, CS-8958, R-125489), the trifluoroacetate (TFA) salt of Laninamivir, is a novel neuraminidase
inhibitor with IC50s of 0.90 nM, 1.83 nM and 3.12 nM for avian H12N5 NA
(N5), pH1N1 N1 NA (p09N1) and A/RI/5+/1957 H2N2 N2 (p57N2),
respectively. It exhibits clinical efficacy for both treatment and
prophylaxis of influenza virus infection, resulting from hydrolytic
bioactivation into its pharmacologically active metabolite laninamivir
in the pulmonary tissue.
纯度:≥98%
CAS:203120-18-7