α-glycosidase-IN-1 (compound MZ7) 是一种有效的α-GLY(α- 糖苷酶)抑制剂,其IC50为 44.72 nM,KI为 41.74 nM。α-glycosidase-IN-1 对人碳酸酐酶同工酶 I 和 II (hCA I和hCA II)以及乙酰胆碱酯酶 (AChE) 也表现出抑制作用,IC50值分别为 104.87、100.04 和 654.87 nM。α-glycosidase-IN-1 可用于糖尿病、阿尔茨海默病、心力衰竭、溃疡、癫痫等多种疾病的研究。
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描述
α-Glycosidase-IN-1 (compound MZ7) is a potent α-GLY (α-Glycosidase) inhibitor, with an IC 50 of 44.72 nM and a K I of 41.74 nM. α-Glycosidase-IN-1 also shows inhibition profile against human carbonic anhydrase isoenzymes I and II ( hCA I and hCA II ), and acetylcholinesterase ( AChE ), with IC 50 values of 104.87, 100.04, and 654.87 nM, respectively. α-Glycosidase-IN-1 can be used for the research of many diseases such as diabetes, Alzheimer’s disease, heart failure, ulcer, and epilepsy [1].
Cas No.
2428389-66-4
分子式
C21H19N9O6S2
分子量
557.56
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years