Folpet 是一种广泛使用的二甲酰亚胺类杀菌剂，可诱发小鼠胃肠道肿瘤，主要发生在十二指肠，对人支气管上皮细胞也有细胞毒作用。

Folpet,a widely used dicarboximide fungicide,induces tumors in the mouse gastrointestinal tract,primarily in the duodenum,and is also cytotoxic effect on human bronchial epithelial cells.

Folpan 80WG particles result in a rapid cytotoxic effect on human bronchial epithelial cells in vitro that could be in part explained by oxidative stress, characterised by membrane lipid peroxidation and ROS production[1].

Sub-confluent 16HBE14o- plated on collagen-coated 60 mm dishes were exposed to Folpan 80WG particles corresponding to 0, 1.85 and 3.70 g/cm^2 folpet (0, 10 and 20 μM) for 2, 4 and 24 h in RPMI-1640 medium w/o phenol red , w/o FCS, supplemented with 1% l-glutamine (200 mM), 1% penicillin (10^4 U/ml), 1% streptomycin (10 mg/ml) and 1% fungizone (25 μg/ml)[1].

133-07-3

C9H4Cl3NO2S

296.55

灭菌丹;Folpet;Faltan

DMSO:125 mg/mL (421.50 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years