HA-155 是一种基于硼酸的化合物,通过选择性结合其催化苏氨酸来抑制 ATX,IC50 为 5.7 nM。
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描述
HA155 is a boronic acid-based compound, inhibiting ATX with IC50 of 5.7 nM by selectively binding to its catalytic threonine.
Cas No.
1229652-22-5
分子式
C24H19BFNO5S
分子量
463.29
别名
Autotaxin Inhibitor IV
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years