Dencichin 是抑制从三七中分到的非蛋白氨基酸,可抑制HIF-prolyl Hydroxylase-2 的活性。
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描述
Dencichine is a neurotoxic agent. Dencichine is a haemostatic agent, the hemostatic effect relates to modulation of the coagulation system, platelet aggregation and fibrinolytic system. It has renoprotective effect, it could significantly prevent the progression of diabetic nephropathy possibly attribute to down-regulation of the TGF-β/Smad pathway and rebalance the deposition and degradation of ECM proteins.
Cas No.
5302-45-4
分子式
C5H8N2O5
分子量
176.128
别名
三七素;L-Dencichin;Dencichin;ODAP
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years