Clofibrate-d4 is the deuterium labeled Clofibrate. Clofibrate is an agonist ofPPAR, withEC₅₀s of 50 μM, ~500 μM for murinePPARαandPPARγ, and 55 μM, ~500 μM for humanPPARαandPPARγ, respectively.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

246.72

C₁₂H₁₁D₄ClO₃

1189654-03-2

氯贝特 d4

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.