Gemfibrozil-d6 (CI-719-d6) is the deuterium labeled Gemfibrozil. Gemfibrozil is an activator ofPPAR-α, used as a lipid-lowering drug; Gemfibrozil is also a nonselective inhibitor of severalP450isoforms, withK_ivalues for CYP2C9, 2C19, 2C8, and 1A2 of 5.8, 24, 69, and 82 μM, respectively.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

256.37

C₁₅H₁₆D₆O₃

1184986-45-5

吉非罗齐 D6

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.