Mildronate (Meldonium) 通过竞争性抑制 BBOX1 和 OCTN2 发挥心脏保护药物的作用。
Cas No. | 76144-81-5 |
别名 | 米屈肼,Meldonium; MET-88; Quaterin |
化学名 | 3-[(trimethylazaniumyl)amino]propanoate |
Canonical SMILES | C[N+](C)(C)NCCC(=O)[O-] |
分子式 | C6H14N2O2 |
分子量 | 146.19 |
溶解度 | ≥ 6.7 mg/mL in Water, ≥ 101.2 mg/mL in EtOH with ultrasonic |
储存条件 | Store at -20℃ |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
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描述 | Mildronate is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption. |