DP-C-4 is aCereblon-based dualPROTACfor simultaneous degradation ofEGFRandPARP^[1].

DP-C-4 (1-50 μM; 24 hours) has degradation effects on EGFR and PARP simultaneously in a dose-dependent manner in SW1990 cells^[1].

1450.93

Solid

C₇₂H₇₈ClF₂N₁₅O₁₄

Room temperature in continental US; may vary elsewhere.

-80°C, stored under nitrogen

DMSO : 12 mg/mL(8.27 mM;Need ultrasonic)

请根据半岛bd体育手机客户端 在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的半岛bd体育手机客户端 失效。
储备液的保存方式和期限：-80℃, 6 months (stored under nitrogen)。-80℃ 储存时，请在 6 个月内使用。