VU 0155069 (CAY10593)，化合物 69，是一种选择性磷脂酶 D1 (PLD1) 抑制剂，体外 IC50 值为 46 nM。 VU 0155069 (CAY10593) 在 transwell 检测中强烈抑制几种癌细胞系的侵袭性迁移。
| Cas No. | 1130067-06-9 |
| 别名 | CAY10593 |
| 化学名 | (S)-N-(1-(4-(5-chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)propan-2-yl)-2-naphthamide hydrochloride |
| Canonical SMILES | ClC1=CC=C2N(C(NC2=C1)=O)C3CCN(C[C@H](C)NC(C4=CC=C5C(C=CC=C5)=C4)=O)CC3.Cl |
| 分子式 | C26H27ClN4O2.HCl |
| 分子量 | 463.0 |
| 溶解度 | DMF: 30 mg/ml ;DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml ; DMSO: 25 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
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