Polyphyllin D - 半岛电竞官方网址

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Polyphyllin D

本半岛bd体育手机客户端不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

半岛bd体育手机客户端介绍

Polyphyllin D 是一种活性皂苷，具有抗癌活性。 Polyphyllin D 诱导 G2/M 细胞周期停滞并引发细胞凋亡。 Polyphyllin D 通过诱导 ROS/NF-κB/NLRP3/GSDMD 信号轴在非小细胞肺癌中诱导 caspase-1 介导的细胞焦亡。

Cas No.	55916-51-3
别名	重楼皂苷VI
化学名	Chonglou saponin VI
Canonical SMILES	O[C@@H]([C@@H](O)[C@H]1O)[C@]([H])(O[C@H]2[C@@](O[C@H]3CC4=CC[C@]([C@](C[C@@](O[C@]5(OC6)CC[C@H]6C)([H])[C@]7(O)[C@@H]5C)([H])[C@@]7(CC8)C)([H])[C@@]8([H])[C@]4(CC3)C)([H])O[C@H](CO)[C@@H](O)[C@@H]2O)C[C@@H]1C
分子式	C₃₉H₆₂O₁₃
分子量	738.91
溶解度	≥ 73.9mg/mL in EtOH with gentle warming
储存条件	Store at -20℃
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端描述	Polyphyllin VI, an active saponin mainly isolated from traditional medicinal plant Paris polyphylla, possess anti-cancer activities. Polyphyllin VI induces G2/M cell cycle arrest and triggers apoptosis[1][2]. References: [1]. Lin Z, et al. Anti-lung Cancer Effects of Polyphyllin VI and VII Potentially Correlate with Apoptosis In Vitro and In Vivo. Phytother Res. 2015 Oct;29(10):1568-76. [2]. Liu Y, et al. Molecular Mechanisms of Apoptosis in HepaRG Cell Line Induced by Polyphyllin VI via the Fas Death Pathway and Mitochondrial-Dependent Pathway. Toxins (Basel). 2018 May 15;10(5). pii: E201.