重组新冠RBD单克隆抗体
| 型号: | MAV101 | | 品牌: | 卡梅德生物 | | 参考价格: | 3500元/ug | | 交货期: | 2-3天 | | 产地: | 天津 |
包装与价格： | 订货号 | 纯度规格 | 包装 | 价格(元) | | MAV101 | | 100ug | 3500 |
半岛bd体育手机客户端
介绍
| 半岛bd体育手机客户端
编号 | MAV101 |
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| 半岛bd体育手机客户端
名称 | Recombinant Human anti-COVID-19/SARS-CoV-2 RBD Monoclonal Antibody |
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| 抗体亚型 | IgG1 |
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| 规格与价格 | 100ul/￥3,500; 500ul/￥9,000; 1000ul/￥16,000 |
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| 克隆号 | 1G6 |
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| 半岛bd体育手机客户端
别名 | SARS-CoV-2 RBD antibody, 2019-nCoV, Coronavirus |
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| 规格 | 100ul, 500ul |
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| 物种 | COVID-19 |
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| 宿主 | Human |
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| 半岛bd体育手机客户端
应用 | ELISA, Colloidal Gold, POCT, Neutralizaiton , Standard Positive Control |
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| 内毒素水平 | <0.1EU/ug determided by LAL method. |
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| 缓冲体系 | 0.01M PBS, pH 7.4 |
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| 免疫原 | Native virus |
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| 半岛bd体育手机客户端
背景 | A novel severe acute respiratory syndrome (SARS)-like coronavirus (SARS-CoV-2) recently emerged and is rapidly spreading in humans, causing COVID-19. A key to tackling this pandemic is to understand the receptor recognition mechanism of the virus, which regulates its infectivity, pathogenesis and host range. SARS-CoV-2 and SARS-CoV recognize the same receptor—angiotensin-converting enzyme 2 (ACE2)—in humans. Researchers determined the crystal structure of the receptor-binding domain (RBD) of the spike protein of SARS-CoV-2 (engineered to facilitate crystallization) in complex with ACE2. In comparison with the SARS-CoV RBD, an ACE2-binding ridge in SARS-CoV-2 RBD has a more compact conformation; moreover, several residue changes in the SARS-CoV-2 RBD stabilize two virus-binding hotspots at the RBD–ACE2 interface. These structural features of SARS-CoV-2 RBD increase its ACE2-binding affinity. Additionally, we show that RaTG13, a bat coronavirus that is closely related to SARS-CoV-2, also uses human ACE2 as its receptor. |
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| 保存条件 | This product can be stored at 2℃-8℃ for one month. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
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| 备注 | This product is used for research use only. Not for human or diagnostic use. |
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卡梅德生物科技（天津）有限公司电话: 点击&查看400-621-6806 /022-82164980 13116038708联系人: 张经理邮编: 301700地址: 天津市武清开发区畅源道国际企业社区 A5 号楼四层
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