蛋白质/抗原/多肽 >> 重组蛋白
重组转录因子HELT蛋白
半岛bd体育手机客户端 介绍
基因名：
Helt 半岛bd体育手机客户端 别名： A830086M02； Hesl； Heslike； Mgn； megane； Helt； helt bHLH transcription factor； helt bHLH transcription factor； hairy and enhancer of split-related protein HELT； HES/HEY-like transcription factor； Hes-like transcription factor； bHLH transcription factor megane； mesencephalic GABAergic neurons enhancer of split related protein； protein megane； 转录因子HELT蛋白； 背景信息：
The Drosophila hairy and Enhancer of split genes encode basic helix-loop-helix (bHLH) transcriptional repressors that function in the Notch signaling pathway and control segmentation and neural development during embryogenesis. The Notch signaling pathway is thought to maintain stem cells through transcriptional activation of HES/HEY family members to repress tissue-specific transcription factors. HESL (HES-like), also known as Mgn or HELT (HES/HEY-like transcription factor), is a 327 amino acid nuclear protein belonging to the HEY family. Containing a basic helix-loop-helix (bHLH) domain and an Orange domain, HESL self-associates and interacts with HES5 and HRT2. HESL is considered a transcriptional repressor that binds to the canonical E box sequence 5'-CACGCG-3'. HESL exists as two isoforms produced by alternative splicing events.
标签：His-tag |
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