蛋白质/抗原/多肽 >> 重组蛋白
重组穿膜蛋白DLK2
半岛bd体育手机客户端 介绍
基因名:
DLK2 半岛bd体育手机客户端 别名: DLK-2; EGFL9; DLK2; delta like non-canonical Notch ligand 2; delta like non-canonical Notch ligand 2; protein delta homolog 2; EGF-like protein 9; EGF-like-domain, multiple 9; delta-like 2 homolog; epidermal growth factor-like protein 9; 穿膜蛋白DLK2; 背景信息:
DLK2 is a 383 amino acid single-pass transmembrane protein with six tandem EGF-like repeats in the putative extracellular domain, which is characteristic of the EGF-like protein family. DLK2 shares nearly identical structural features with DLK, suggesting that it may function in a similar way. Like DLK, DLK2 affects adipogenesis of 3T3-L1 preadipocytes and mesenchymal C3H10T1/2 cells, yet it does so in an opposite way to that of DLK. Also, expression of DLK and DLK2 are inversely correlated and changes in expression of one gene will affect the expression levels of the other. Therefore, it is likely that adipogenesis is modulated by the coordinated expression of DLK and DLK2. There are two isoforms of DLK2 that are produced as a result of alternative splicing events.
标签:His-tag |
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