蛋白质/抗原/多肽 >> 重组蛋白
重组ATP依赖的解旋酶CHD8蛋白
半岛bd体育手机客户端 介绍
基因名：
CHD8 半岛bd体育手机客户端 别名： AUTS18； HELSNF1； IDDAM； CHD8； chromodomain helicase DNA binding protein 8； chromodomain helicase DNA binding protein 8； chromodomain-helicase-DNA-binding protein 8； ATP-dependent helicase CHD8； axis duplication inhibitor； duplin； helicase with SNF2 domain 1； ATP依赖的解旋酶CHD8； 染色质域解旋酶DNA结合蛋白8(CHD8)； 背景信息：
This gene encodes a DNA helicase that functions as a transcription repressor by remodeling chromatin structure. It binds beta-catenin and negatively regulates Wnt signaling pathway, which plays a pivotal role in vertebrate early development and morphogenesis. Mice lacking this gene exhibit early embryonic death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]
标签：His-tag |
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