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重组端粒酶结合蛋白EST1A
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介绍 基因名: SMG6 半岛bd体育手机客户端 别名: C17orf31; EST1A; SMG-6; hEST1A; hSMG5/7a; SMG6; SMG6 nonsense mediated mRNA decay factor; SMG6 nonsense mediated mRNA decay factor; telomerase-binding protein EST1A; EST1 telomerase component homolog A; ever shorter telomeres 1A; nonsense mediated mRNA decay factor SMG6; smg-6 homolog, nonsense mediated mRNA decay factor; telomerase subunit EST1A; 端粒酶结合蛋白EST1A; 背景信息: This gene encodes a component of the telomerase ribonucleoprotein complex responsible for the replication and maintenance of chromosome ends. The encoded protein also plays a role in the nonsense-mediated mRNA decay (NMD) pathway, providing the endonuclease activity near the premature translation termination codon that is needed to initiate NMD. Alternatively spliced transcript variants encoding distinct protein isoforms have been described. [provided by RefSeq, Feb 2014] 标签:His-tag |
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