蛋白质/抗原/多肽 >> 重组蛋白
重组微管相关肿瘤抑制蛋白2
半岛bd体育手机客户端 介绍
基因名:
MTUS2 半岛bd体育手机客户端 别名: CAZIP; ICIS; KIAA0774; TIP150; MTUS2; microtubule associated scaffold protein 2; microtubule associated scaffold protein 2; microtubule-associated tumor suppressor candidate 2; +TIP of 150 kDa; cardiac zipper protein; microtubule associated tumor suppressor candidate 2; microtubule plus-end tracking protein TIP150; tracking protein of 150 kDa; 微管相关肿瘤抑制蛋白2; 背景信息:
Comprising nearly 4% of human DNA, chromosome 13 contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections. The KIAA0774 gene product has been provisionally designated KIAA0774 pending further characterization
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