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重组驱动蛋白家族成员1B
半岛bd体育手机客户端
介绍 基因名: Kif1b 半岛bd体育手机客户端 别名: A530096N05Rik; AI448212; AI506502; D4Mil1e; KIF1Bp130; KIF1Bp204; Kif1b; kinesin family member 1B; kinesin family member 1B; kinesin-like protein KIF1B; N-3 kinesin; kinesin heavy chain member 1B; 驱动蛋白家族成员1B; 背景信息: KIF1B, or kinesin-like protein (Klp) functions as a motor for mitochondrial transport, and has a microtubule plus end-directed motility. The KIF1B beta isoform is abundant in brain, while the alpha isoform is abundant in skeletal muscle. Mutations in the KIF1B gene are the cause of Charcot-Marie-Tooth disease type 2A1, which is a primary peripheral axon neuropathy. The KIF1B beta isoform is down-regulated in sporadic amyotrophic lateral sclerosis (ALS). 标签:His-tag |
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